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Cell culture is an indispensable tool in a variety of biological applications, such as cell biology/physiology studies, drug screening, toxin testing, and other cell-based assays. The most widely used cell-culture practice nowadays is to culture cells using multi-well microplates or Petri dishes as culture vessels. With the advent of highly throughout automated micro- and mini-bioreactors, cells can be produced at large scale and with high quality under controlled conditions in a short period of time. However, more and more cell culture systems are designed not only for cell proliferation but also for performing specific cell-based assays.

By improving the design of cell culture system, the parameters such as dissolved oxygen concentration, pH value and osmotic pressure of cell culture medium can be controled. For either adherent or suspension cell cultures, the culture vessel may directly or indirectly influence the cues provided from the microenvironment through chemical or mechanical stimuli. The physicochemical properties of the culture material may affect the type, amount, and conformation of proteins and other media components adsorbed to the culture vessel. In addition to changing the shear forces exerted on the cells during treatment, the topography and stiffness of the culture vessel can change the cell interactions with surface. All of these factors can significantly change the cellular microenvironment, potentially acting synergistically, and altering product quality.

The selection of an appropriate cell culture system is thus important for the design and development of cell production or cell-based biochemical research strategies. Amerigo Scientific offers cell culture systems with different materials and functions, as well as other cell culture-related products to meet different research needs.