Diffusion is the main mode of mass transfer in porous particle chromatography. In polydisperse media, the uneven diffusion pathlength between particles of different sizes and shapes leads to slow mass transfer rate, long elution time, and band broadening, resulting in a loss of chromatographic column efficiency. These limitations can be overcome by using spherical monodisperse media with similar diffusion path lengths.
Amerigo Scientific provides monodisperse chromatographic media for high performance liquid chromatography (UPLC and HPLC), process-scale purification, and solid phase extraction (SPE) sample preparation. These media of spherical monodisperse particles are manufactured utilizing world leading technology in an ISO-9001-certified facility for the purification of proteins, enzymes, antibodies, viruses, and other substances.
Developed using unique patented technology, the chromatographic media are characterized by uniform particle size, perfect sphericity, excellent mechanical strength, which give the products advantages in chromatographic applications including high efficiency, robust packaging and repackaging, quality consistency, etc.
Features
- Rigorous manufacturing process and large-scale production
- Uniformed particle size and perfectly spherical shape
- Optimal pore structure
- Unique selectivity
- Lower back pressure
- Less risk for fouling or clogging for longer lifetime
- Possible to use larger mesh size filters/nets
Benefits
- High consistency and repeatability between batches
- High column efficiency, low plugging risk for frits
- Better column integrity and efficiency (HETP & asymmetry)
- High loading capacity
- Higher resolution
- Faster mass transfer, more concentrated elution, and less buffer consumption
- Robust column packing and repacking, long lifetime
Product Range
HILIC Silica Gels
A new generation of hydrophilic interaction liquid chromatography media
Polymeric Chromatography Media
Affinity Chromatography Resins
Solid Phase Extraction Sorbents
Applications
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