Diffusion is the main mode of mass transfer in porous particle chromatography. In polydisperse media, the uneven diffusion pathlength between particles of different sizes and shapes leads to slow mass transfer rate, long elution time, and band broadening, resulting in a loss of chromatographic column efficiency. These limitations can be overcome by using spherical monodisperse media with similar diffusion path lengths.
Amerigo Scientific provides monodisperse chromatographic media for high performance liquid chromatography (UPLC and HPLC), process-scale purification, and solid phase extraction (SPE) sample preparation. These media of spherical monodisperse particles are manufactured utilizing world leading technology in an ISO-9001-certified facility for the purification of proteins, enzymes, antibodies, viruses, and other substances.
Developed using unique patented technology, the chromatographic media are characterized by uniform particle size, perfect sphericity, excellent mechanical strength, which give the products advantages in chromatographic applications including high efficiency, robust packaging and repackaging, quality consistency, etc.
Ultra-high purity monodisperse silica microspheres
A new generation of hydrophilic interaction liquid chromatography media
Reversed phase silica gels based on monodisperse UniSil® media
Polymeric resins for reversed phase chromatography
Resins with charged functional groups that attract biomolecules with opposite charges
Chemically modified highly crosslinked polymethacrylate resin beads
Rigid, mono-sized polymethacrylate matrices for purification of antibodies
Resins for purifying proteins based on the affinity of certain amino acids to specific metal ions
Affinity media for the selective separation and purification of cis-diol containing compounds
Affinity chromatography resins for purification of biological substances
Specialty monodisperse microspheres with good chemical stability, broad pH range, and optimized surface functional groups