MagTouch Magnetic Nucleic Acid Purification Instruments
MagTouch 2000 is an automatic system for the extraction and purification of nucleic acids from various types of biological samples collected in a variety of transport media. The automatic instrument absorbs, transfers and releases magnetic beads through magnetic rods and magnetic rod sleeves to separate magnetic beads from samples. The operation is fast and simple. For fast extraction and purification of nucleic acids from various kinds of biological samples, MagTouch 2000 instruments are available in 24-well and 96-well formats.
Features of MagTouch 2000
- High-throughput automation system for nucleic acid extraction
- Programmable procedure and precise temperature control
- Color touchscreen interface and one-button start
- Removable transparent cover for automatic liquid transfer workstation
- Build-in UV light for sterilization
- Turntable for up to 8 plates and working time per run of about 30 minutes to 90 minutes
- The vibration of the magnetic head automatically matches the volume of the reagent during mixing
Modules in MagTouch 2000
| Modules |
Functions |
| Plastic tip comb module |
mixing; transfer magnetic beads |
| Magnetic head module |
magnetization of beads |
| Turntable module |
switch of plates |
| Thermal module (optional) |
temperature control |
| Shield module |
prevent potential cross contamination |
| UV sterilization module |
sterilization |
| Working lamp module |
illumination |
Downstream Applications of MagTouch 2000
- Next-generation sequencing (NGS)
- Droplet digital PCR (ddPCR)
- Real Time PCR (qPCR)
- DNA methylation analysis
- Cell-free chromatin immunoprecipitation (cfChIP)
High Efficiency cfDNA Isolation Using MagTouch 2000
MagTouch 2000 Nucleic Acids Extraction Automation System can be utilized to extract cell-free DNA (cfDNA) from various volumes of plasma samples. Circulating cfDNA is non-encapsulated form of double-stranded DNA with an average size of 150 to 180 bp, likely derived from apoptosis, necrosis, and to a lesser extent, active secretion. cfDNA has a lifespan of less than 2 hours before being filtered eliminated from the bloodstream by the spleen, liver, and kidneys. In healthy individuals, cfDNA is mainly derived from apoptotic cells, and the lengths of the DNA fragments are usually around 185 to 200 bp. In cancer tissue, the size of cfDNA is highly variable because, in addition to apoptosis, necrosis and autophagy are causes of cancer cell death. In this case, the DNA fragments can reach 450 to 500 bp.
The MagTouch 2000 instrument can be used with our MiniMax High Efficiency Cell-Free DNA Isolation Kit to automate the cfDNA isolation process and significantly improve the lab flow and efficiency. The MiniMax High Efficiency Cell-Free DNA Isolation Kit provides highly efficient and reproducible recovery of high-quality cfDNA with high yield. The isolated DNA samples are suitable for a broad range of subsequent applications, including sequencing, PCR, etc.
Viral Total Nucleic Acid Isolation Using MagTouch 2000
MagTouch 2000 automation system can be used with our MiniGenomics Viral Total Nucleic Acid (NA) Isolation Kit for the rapid extraction and purification of viral nucleic acid from various biological samples (such as swabs, saliva, and blood) collected in multiple transport media, achieving highly efficient, reproducible recovery of high-quality DNA and RNA with high yield.
Working Conditions of MagTouch 2000
MagTouch 2000 should be placed in a place with minimal dust, away from humidity and direct sunlight. The installation location should be well ventilated, away from electromagnetic interference and heat sources. The vent on this instrument is designed for ventilation, so do not cover to prevent overheating.
| Conditions |
Requirements |
| Input voltage |
AC 100-240 V, 50Hz / 60Hz |
| Surrounding temperature |
10°C to 35°C |
| Humidity |
below 70% |
| Atmosphere pressure range |
500 hPa to 1060 hPa |
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