UniSil® hydrophilic interaction liquid chromatography (HILIC) silica gel is a new generation of HILIC media developed through unique surface passivation and bonding technologies with multiple functions such as hydrophilic, separation and distribution. Moreover, solutions containing up to 60% H2O can be used as the mobile phase of the medium.
Many high polarity substances have too weak retentivity in reversed-phase chromatography to be separated (k≈0), but can be easily separated using hydrophilic interaction chromatography. Compared to reversed silica gel, UniSil® HILIC silica gel is a better choice for highly polar and hydrophilic molecules, especially strongly alkaline chemicals, with a high proportion of volatile mobile phases that can improve the sensitivity of LC-MS.
Product Name | Cat. No. | Particle Diameter | Pore Size | Size |
---|---|---|---|---|
UniSil® 5-120 HILIC-T | 19012-050012 | 5 μm | 120 Å | 10g; 50g; 100g; 500g; 1kg |
UniSil® 5-120 HILIC-2M | 19011-050012 | 5 μm | 120 Å | 10g; 50g; 100g; 500g; 1kg |
UniSil® 5-120 Amide | 19017-050012 | 5 μm | 120 Å | 10g; 50g; 100g; 500g; 1kg |
UniSil® 10-120 HILIC-T | 19012-100012 | 10 μm | 120 Å | 100g; 500g; 1kg; 5kg; 10kg; 20kg |
UniSil® 10-120 HILIC-2M | 19011-100012 | 10 μm | 120 Å | 100g; 500g; 1kg; 5kg; 10kg; 20kg |
UniSil® 10-120 Amide | 19017-100012 | 10 μm | 120 Å | 100g; 500g; 1kg; 5kg; 10kg; 20kg |
Application of UniSil® 5-120 HILIC-2M for using pure H2O as mobile phase
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