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  • Amerigo Scientific Instrument

    • UniMab® Protein A Affinity resins are designed to raise the purification efficiency of monoclonal antibodies (mAb) and recombinant Fc fragment proteins. The resins are based on rigid, mono-sized polymethacrylate matrices with good surface hydrophilicity, minimal non-specific binding and high mechanical strength for fast flow operations. With excellent FC binding selectivity and base stability, UniMab® Protein A Affinity resins have proven its strong properties in many successful applications including bioprocess purification of mAb-drugs in phase III.

    Products

    Product Name Cat. No. Particle Diameter Pore Size Size
    UniMab 50 17010-050100 50 μm   30ml; 100ml; 500ml; 1L; 10L

    Highlights

    • Suitable for columns with higher bed height
    • High dynamic binding capacity (DBC) and high recovery yield
    • Minimal non-specific binding
    • Superior alkaline stability
    • High reproducibility
    • Low concentration host cell protein (HCP) and low level of protein A leachate

    Features

    Matrix Mono-sized Polymethacrylate
    Ligand Engineered rProtein A
    Particle size, µm 50
    Loading, mg human IgG/ml packing (4 min residence time) >35
    Maximum pressure, psi (bar, MPa) 116 (8,0.8)
    Maximum flow rate, cm/h 800
    Protein A leachate < 5 ng/ml
    pH stable range 3-12
    CIP cleaning 0.1-0.5M NaOH
    Temperature, °C 4-40
    Storage 20% Ethanol, 2-8 °C

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