In the field of life sciences, probes are a key tool specifically designed to identify and detect biomolecules and their dynamic changes. Probes can convert microscopic molecular events into visual and quantifiable signals by highly specifically binding to target molecules such as DNA, RNA, proteins, ions, and metabolites, thereby achieving accurate detection of cell activities, molecular interactions, and life processes. Probes are indispensable basic tools for modern biological and medical research, and they are widely applied in gene expression analysis, protein function research, cell imaging, disease diagnosis, and drug screening.
According to different targets and application scenarios, probes can be divided into nucleic acid probes, protein probes, living cell probes, ion and metabolic probes, optical and magnetic probes, and bioorthogonal probes. These types of probes meet multi-level research needs from the molecular level to the cell, tissue and system level. The probes can be labeled with diverse signal systems-including fluorescence, enzymatic activity, radioisotopes, and magnetic properties-and are compatible with various detection platforms such as fluorescence microscopy, flow cytometry, qPCR, and magnetic resonance imaging. As scientific research continues to develop towards high throughput, high sensitivity, spatialization, and single-cellization, probe technology continues to evolve, with higher signal-to-noise ratios, stronger biocompatibility, and more flexible chemical design.
Amerigo Scientific provides a variety of high-performance probes to meet a variety of needs ranging from molecular labeling, targeted identification to functional research, supporting precision medicine, targeted therapy, and systems biology research.
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