PTM-Specific Antibody Products

PTM-Specific Antibody Products


Background

Post-translational modifications (PTMs) are critical biochemical alterations that occur to proteins after their synthesis. These modifications can dramatically influence protein function, stability, localization, and interactions. At Amerigo Scientific, we are proud to offer a comprehensive range of PTM-specific antibody products designed to empower researchers in their quest to unravel these intricate biological mechanisms.

Protein Post-translational Modifications

PTMs play a crucial role in regulating various cellular functions, including the function, localization, and stability of proteins within cells. Some common PTMs include phosphorylation, glycosylation, acetylation, methylation, ubiquitination, and sumoylation. The dynamic nature of these modifications allows cells to respond quickly to environmental changes, making them key players in cellular signaling pathways. However, studying these modifications requires specialized tools. At Amerigo Scientific, we recognize the significance of PTMs in cellular processes and have developed a range of PTM-specific antibody products to support researchers in their quest to unravel the complexities of protein biology.

Fig.1 Common post-translational modifications. Fig.1 Overview of the most common PTMs.1

PMT Antibody Products

Amerigo Scientific provides an array of research tools and resources that aim to advance the understanding of PTMs and their impact on cellular signaling pathways and disease mechanisms. We offer a comprehensive range of PTM antibody products that are designed to recognize and target certain post-translational modifications on proteins. These antibodies have been rigorously validated for specificity and sensitivity in detecting PTMs. Our products include phospho-specific antibodies, specifically tailored for the detection of phosphorylated proteins, as well as acetyl-specific antibodies that allow researchers to target acetylated proteins. These antibodies are valuable tools for studying PTMs, as they can be used for various applications such as western blotting, immunoprecipitation, and immunofluorescence to detect and quantify specific PTMs in cells and tissues.

Phospho-Specific Antibodies

Phosphorylation is the most common PTM of proteins. We offer a wide variety of phospho-specific antibodies for the investigation of protein phosphorylation. These off-the-shelf antibodies target proteins that are phosphorylated at specific amino acid sites, including serine, threonine, or tyrosine. Our phospho-specific antibodies are rigorously tested to ensure accurate and reliable detection of phosphorylated proteins.

Acetyl-Specific Antibodies

Acetyl-specific antibodies are specialized tools used for studying protein acetylation. We provide researchers with acetyl-specific antibodies to advance their understanding of protein acetylation and its implications in health and disease. These antibodies specifically recognize and bind to acetylated lysine residues, allowing researchers to investigate the presence and abundance of acetylation on specific proteins in a sample.

Amerigo Scientific’s PTM-specific antibody products represent a vital resource for researchers aiming to elucidate the roles of PTMs in biological systems. Please browse and explore our range of PTM-specific antibodies today! If you want more information about our PTM antibody products, please contact us.

Reference

  1. Abdeldaim, Dalia T., and Katharina Schindowski. "Fc-engineered therapeutic antibodies: recent advances and future directions." Pharmaceutics 15.10 (2023): 2402. Distributed under Open Access license CC BY 4.0, without modification.

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