Full Name: C-X-C Motif Chemokine Ligand 10
BACKGROUND: This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection.
Synonyms: C7; IFI10; INP10; IP-10; SCYB10; crg-2; gIP-10; mob-1
Research Areas: Immunology
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