Full Name: General control transcription factor GCN4
BACKGROUND: Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II-specific DNA-binding transcription factor binding activity; and chromatin binding activity. Involved in several processes, including positive regulation of cellular response to amino acid starvation; protein localization to nuclear periphery; and regulation of transcription by RNA polymerase II. Located in nucleus. Human ortholog(s) of this gene implicated in pulmonary tuberculosis.
Synonyms: GCN4; AAS3; ARG9; General control protein GCN4; Amino acid biosynthesis regulatory protein
Research Areas: Microbiology
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