FCRL1

Full Name: Fc Receptor Like 1

BACKGROUND: This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants.

Synonyms: FCRL1; Fc receptor-like 1; FCRH1; IFGP1; IRTA5; CD307a; Fc receptor-like protein 1; hIFGP1; fcR-like protein 1; IFGP family protein 1; fc receptor homolog 1; immunoglobulin superfamily Fc receptor, gp42; immune receptor translocation-associated protein 5