Full Name: Desmoglein 2
BACKGROUND: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein.
Synonyms: Desmoglein 2; Cadherin Family Member 5; CDHF5; HDGC; Desmoglein-2
Research Areas: Signal Transduction
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