Full Name: FBXW7 Antisense RNA 1
BACKGROUND: Dual endothelin-1/VEGFsp receptor (DEspR) is a common target on tumor vascular endothelial cells (TVECs), tumor cells (TCs), and cancer stem cells (CSCs) in glioblastoma and pancreatic cancer. It's inhibition provides a potential therapeutic strategy for simultaneous inhibition of multiple pro-malignancy steps: angiogenesis, invasiveness, and anoikis resistance.
Synonyms: DEspR; Dual endothelin1/VEGFsp receptor; FBXW7-AS1
Research Areas: Cancer
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