Full Name: CD80 antigen
BACKGROUND: Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.
Synonyms: CD80; B7.1; CD28LG1; T-Lymphocyte Activation Antigen CD80; CD80 Molecule; CD80 Antigen; B-Lymphocyte Activation Antigen B7; CTLA-4 Counter-Receptor B7.1; Costimulatory Molecule Variant IgV-CD80; CD28LG; BB1; Costimulatory Factor CD80
Research Areas: Immunology
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