Full Name: HLA class II histocompatibility antigen gamma chain
BACKGROUND: HLA-DR is a type of HLA class II molecule, a cell surface protein expressed on antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. HLA-DR presents peptide fragments derived from extracellular proteins to helper T cells (CD4+ T cells), initiating and regulating adaptive immune responses.
Synonyms: HLA-DR; HLA class II histocompatibility antigen gamma chain
Research Areas: Immunology
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