In Vivo Antibody Products

What Are In Vivo Antibodies

In vivo antibodies are essential biological tools used in a variety of biological and medical research. These antibodies are specifically designed for in vivo use, meaning they are intended for use inside a living organism. Compared to in vitro antibodies, they require more stringent manufacturing and testing standards to ensure their suitability for use within a living organism. The features of in vivo antibodies include high purity, low endotoxin levels, very low aggregation, and no azide or other cytotoxic preservatives. They are used in a variety of studies including vaccination studies, depletion or blocking of certain cell populations, and therapeutic antibody production.

Features of Our In Vivo Antibodies

The requirements for in vivo antibodies are more stringent compared to in vitro antibodies.

• Stability: In vivo antibodies need to exhibit high stability under the physiological conditions in the living body.
• Immunogenicity: Ideally, in vivo antibodies should induce a minimal immune response in the host.
• Bioavailability: In vivo antibodies must effectively reach their target sites in the body. This requires antibodies to have excellent circulatory properties and a long half-life time.
• Toxicity: In vivo antibodies should have negligible or low toxicity to the body to prevent collateral damage to healthy cells and tissues.
• Specificity: In vivo antibodies are designed to target specific antigens present in living organisms. They bind to these antigens with high specificity to provide effective therapeutic response.

Available In Vivo Antibodies

Amerigo Scientific is your trusted supplier of monoclonal and polyclonal antibodies. As a company dedicated to contributing to scientific research and medical advancements, we are excited to launch our line of in vivo antibody products. Our in vivo antibodies are manufactured through a rigorous process that ensures their purity, affinity, and minimal lot-to-lot variance. Whether you're studying the immune response, cancer research, or infectious diseases, our in vivo antibodies offer you the reliability and specificity you need. Our antibodies are used in various biotechnological applications, such as WB, immunoprecipitation, immunohistochemistry, blocking, flow cytometry, and functional assays.

Production and Quality Control

• Protein A or G affinity purification
• High purity: Purity ≥ 95% as determined by SDS-PAGE or SEC-HPLC
• 0.22µm sterile filtered
• Low endotoxin levels: <1.0 EU/mg to <0.1 EU/mg as determined by the LAL method
• High concentration: 1.0 mg/mL to 5.0 mg/mL
• Aggregation: Aggregation level ≤ 5%
• PBS formulation without preservatives, stabilizers, or carrier protein