Full Name: Severe acute respiratory syndrome coronavirus 2 Spike protein
BACKGROUND: The Receptor Binding Domain (RBD) is a specific region of the Spike (S) protein of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This domain directly binds to the angiotensin-converting enzyme 2 (ACE2) receptor on human cells, mediating the initial attachment of the virus and subsequent entry. It is a primary target for vaccines and therapeutic antibodies.
Synonyms: SARS-CoV-2; SARS-CoV-2 S RBD; Spike glycoprotein
Research Areas: Microbiology
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