Full Name: Interleukin 33
BACKGROUND: The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms: IL33; interleukin 33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26
Research Areas: Immunology
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