Full Name: lymphocyte antigen 6 family member E
BACKGROUND: This gene belongs to the human Ly6 gene family and encodes a glycosylphosphatidyl-inositol (GPI)-anchored cell surface protein. The protein plays an important role in T cell physiology, oncogenesis and immunological regulation. The protein is also involved in modulation of viral infection by coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2.
Synonyms: RIGE; SCA2; RIG-E; SCA-2; TSA-1
Research Areas: Cell Biology
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