Full Name: T Cell Immunoreceptor With Ig And ITIM Domains
BACKGROUND: This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
Synonyms: VSIG9; VSTM3; WUCAM
Research Areas: Immunology
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