ATP6AP2

Full Name: ATPase H+ Transporting Accessory Protein 2

BACKGROUND: This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases-F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.

Synonyms: ATPase H+ Transporting Accessory Protein 2; Vacuolar ATP Synthase Membrane Sector-Associated Protein M8-9; ATPase, H+ Transporting, Lysosomal Interacting Protein 2; ATPase H(+)-Transporting Lysosomal-Interacting Protein 2; ATPase, H+ Transporting, Lysosomal Accessory Protein 2; Embryonic Liver Differentiation Factor 10; ER-Localized Type I Transmembrane Adaptor; Renin/Prorenin Receptor; V-ATPase M8.9 Subunit; Prorenin Receptor; Renin Receptor; ATP6M8-9; ATP6IP2; ELDF10; N14F