Full Name: Signal Regulatory Protein Gamma
BACKGROUND: The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms: CD172g; SIRP-B2; SIRPB2; SIRPgamma; bA77C3.1
Research Areas: Immunology
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