Full Name: Reovirus type 3 Outer capsid protein sigma-1
BACKGROUND: The sigma 1 (σ1) protein is an outer capsid protein of Reovirus type 3. It acts as the viral attachment protein, binding to specific receptors on host cells (such as the junctional adhesion molecule-1, JAM-1). This interaction determines viral tropism and is important for pathogenesis.
Synonyms: S1; Outer capsid protein sigma-1; Sigma1; Cell attachment protein; Hemagglutinin
Research Areas: Microbiology
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