Full Name: Fc Fragment Of IgE Receptor II
BACKGROUND: The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms: BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF
Research Areas: Immunology
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