Anti-CD3E Monoclonal Antibody (UCHT1)

Anti-CD3E Monoclonal Antibody (UCHT1)

Cat No: ASPC002

Summary
Host Species:
Mouse
Species Reactivity:
Human, Non-Human Primates, Chimpanzee
Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunofluorescence, Activation, Blocking
Clone ID:
UCHT1
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC002 Anti-CD3E Antibody (UCHT1) Mouse IgG1, Kappa None $460 In stock
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ASPC002-1 Anti-CD3E Antibody (UCHT1), Fab fragment Mouse Fab His tag None $460 In stock
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ASPC002-P Anti-CD3E Antibody (UCHT1), PE Mouse IgG1, Kappa PE $1,180 2-3 weeks
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ASPC002-A Anti-CD3E Antibody (UCHT1), APC Mouse IgG1, Kappa APC $980 2-3 weeks
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ASPC002-H Anti-CD3E Antibody (UCHT1), HRP Mouse IgG1, Kappa HRP $600 2-3 weeks
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ASPC002-B Anti-CD3E Antibody (UCHT1), Biotin Mouse IgG1, Kappa Biotin $680 2-3 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-CD3E Monoclonal Antibody (UCHT1)
    • Product Description:
      The UCHT1 antibody specifically binds to the epsilon (ε) chain of the CD3 complex, which is part of the T-cell receptor (TCR) complex. UCHT1 binds to an epitope on the extracellular domain of the CD3 epsilon chain. This binding is critical for its ability to activate T-cells and modulate immune responses.
      Applications:
      Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunofluorescence, Activation, Blocking
      Source:
      Mouse
      Target:
      CD3E
      Target Species:
      Human
      Specificity:
      Human CD3E
      Immunogen:
      Human peripheral blood lymphocytes and infant thymocytes
      Clonality:
      Monoclonal
      Clone ID:
      UCHT1
      Isotype:
      Mouse IgG1, Kappa
      Purification:
      The antibody was purified by Protein A.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for customized product form or formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-CD3E Monoclonal Antibody (UCHT1) Applications
    • Recommended Dilution:
      Flow Cytometry 1 µg/test
      Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
CD3E
Protein Name
T-cell surface glycoprotein CD3 epsilon chain
Molecular Family
CD Molecules, TCRs
Introduction
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency.
Alternative Names
CD3e Molecule; CD3e Antigen, Epsilon Polypeptide (TiT3 Complex); T-Cell Surface Antigen T3/Leu-4 Epsilon Chain; CD3e Molecule, Epsilon (CD3-TCR Complex); T3E; T-Cell Antigen Receptor Complex, Epsilon Subunit Of T3
Gene ID
UniProt
Related Disease
Immunodeficiency 18 (IMD18)
Subcellular Location
Cell membrane
Cell Type
NKT cells, T cells, Thymocytes, Tregs
Function
TCR signal transduction, T cell activation
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