FcRn

Full Name: Fc fragment of IgG receptor and transporter

BACKGROUND: An Fc receptor is a protein found on the surface of certain cells that contribute to the protective functions of the immune system. Its name is derived from its binding specificity for a part of an antibody known as the Fc (Fragment, crystallizable) region. Fc receptors bind to antibodies that are attached to infected cells or invading pathogens. Their activity stimulates phagocytic or cytotoxic cells to destroy microbes, or infected cells by antibody-mediated phagocytosis or antibody-dependent cell-mediated cytotoxicity.

Synonyms: FcRn; Fc receptor FcRn