Full Name: Transferrin Receptor
BACKGROUND: This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Diseases associated with TFRC include Immunodeficiency 46 and Combined T Cell And B Cell Immunodeficiency. Among its related pathways are Hematopoietic cell lineage and Insulin receptor recycling.
Synonyms: T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46
Research Areas: Cancer
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