Full Name: Transmembrane Protease, Serine 4
BACKGROUND: This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain.
Synonyms: Transmembrane Protease, Serine 4; Membrane-Type Serine Protease 2; Type II Membrane Serine Protease; Transmembrane Serine Protease 3; Channel-Activating Protease 2; TMPRSS3; MT-SP2
Research Areas: Neuroscience
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