Full Name: Middle East respiratory syndrome coronavirus S protein
BACKGROUND: The Spike (S) glycoprotein of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a large transmembrane protein on the surface of the virus. It mediates the crucial first step of infection by binding to the DPP4 receptor on host cells, allowing viral entry. The S protein is a key target for vaccine and therapeutic development.
Synonyms: MERS-CoV Spike protein; Middle East respiratory syndrome coronavirus S protein; MERS-CoV S
Research Areas: Microbiology
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