Full Name: Jagged canonical Notch ligand 1
BACKGROUND: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Synonyms: AGS; AHD; AWS; HJ1; AGS1; CD339; JAGL1
Research Areas: Cardiovascular Biology
Amerigo scientific offers a comprehensive range of antibodies target JAG1. Use the filter to find the JAG1 antibody that best fits your needs.
