Full Name: Interleukin 17F
BACKGROUND: The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1.
Synonyms: Interleukin 17F; Cytokine ML-1; IL-17F; CANDF6; ML-1; ML1
Research Areas: Immunology
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