Stem Cell Marker related Antibody Products

Stem Cell Marker related Antibody Products


Background

Amerigo Scientific is steadfastly dedicated to furnishing an exhaustive and meticulously curated antibody product catalog within the intricate and dynamic field of stem cell research.

Overview of Stem Cell Markers

Stem cells are a group of cells that have not yet fully differentiated. Therefore, these cells have great potential to develop into diverse organs and tissues. These cells are usually found in multicellular tissues and are capable of dividing into a series of specialized cells. Typically, stem cells develop into a series of progenitor cells that further mature along specific lineages. Stem cell markers play a pivotal role in identifying and isolating stem cells in different cell types. Therefore, these markers are commonly used to identify embryonic stem cells (ESCs), mesenchymal stem cells (MSCs), hematopoietic stem cells (HSCs) as well as neural stem cells (NSCs).

Fig.1 Lung cancer markers. Fig.1 Potential lung cancer stem cell with its markers and major signaling pathways.1

ESC Markers

ESCs are the most pluripotent cell population with the greatest developmental potential. ESC markers are factors that are specifically expressed in ESCs. Fully characterizing the functions of these markers is conducive to clarifying the mechanisms of ESC pluripotency maintenance and self-renewal, thereby accelerating the clinical application of ESCs.

  • CD15
  • SSEA-3
  • SSEA-4
  • CD31
  • CD324
  • CD90
  • CD117
  • TRA-1-60
  • CD326
  • CD9
  • CD29
  • TRA-1-81
  • CD59
  • CD133
  • CD24

MSC Markers

MSCs are a group of multipotent stem cells isolated from the umbilical cord, adipose tissue, bone marrow, adipose tissue, and fetal liver. MSCs have the properties of self-renewal ability and multi-lineage differentiation potential. Currently, MSCs play a vital role in clinical research.

  • BMPR1A
  • BMPR1B
  • BMPR2
  • CD54
  • CD56
  • CD105
  • CD106
  • CD117
  • CD73
  • CD90
  • CD13
  • CD166
  • CD29
  • CDH2
  • FN1
  • CD349
  • CD44
  • CD45
  • HLA-G
  • NGFR
  • CD49a
  • CD49e
  • CD51
  • SUSD2
  • TFRC

HSC Markers

HSCs are capable of producing other blood cells. A variety of blood cells originate from HSCs, such as macrophages, monocytes, red blood cells, T cells, and B cells.

  • ATXN1
  • CD105
  • CD110
  • CD111
  • CD117
  • CD133
  • CD135
  • CD150
  • CD184
  • CD202b
  • CD243
  • CD244
  • CD271
  • CD309
  • CD338
  • CD34
  • CD38
  • CD4
  • CD48
  • CD90

NSC Markers

NSCs, a group of self-renewing multipotent cells, are also progenitor cells in the central nervous system. NSCs generate the neurons and glial cells that underlie all animal nervous systems. In addition, NSCs also play crucial functions in neuroinflammation and neurodegenerative diseases.

  • ABCG2
  • CD133
  • CXCR4
  • Glut1
  • ASCL1
  • BMI1
  • CALCR
  • CDCP1
  • CDH2
  • CTNNB1
  • FABP7
  • FGFR2
  • FGFR4
  • FOXD3
  • FZD9
  • GATA2
  • GCNF
  • GFAP
  • HOXB1
  • ID2
  • LRTM1
  • METRN
  • MSX1
  • NES
  • NEUROD1
  • NFE2L2
  • NGFR
  • NOTCH1
  • NOTCH2
  • NR2F1
  • NUMB
  • OTX2
  • PAX3
  • PAX6
  • PDGFRA
  • PRKCZ
  • PROM2
  • ROR2
  • RUNX1
  • RXRA
  • SFRP2
  • SLC2A1
  • SMARCA4
  • SOX1
  • SOX11
  • SOX2
  • SOX21
  • SOX9
  • TRAF4
  • VIM
  • ZIC1

As a trusted supplier to many research institutions, Amerigo Scientific is committed to providing global customers with a comprehensive antibody product catalog in the field of stem cell research. Contact Amerigo Scientific for more details on stem cell antibodies.

Reference

  1. Zheng, Yue, et al. "Lung cancer stem cell markers as therapeutic targets: an update on signaling pathways and therapies." Frontiers in Oncology 12 (2022): 873994. 1. Tang, Yuewen, Pei Yu, and Lin Cheng. "Current progress in the derivation and therapeutic application of neural stem cells." Cell death & disease 8.10 (2017): e3108-e3108. Distributed Open Access license CC BY 4.0, without modification.

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