Full Name: Thomsen-Friedenreich Antigen
BACKGROUND: The Thomsen-Friedenreich antigen (TFA) is an O-linked carbohydrate structure composed of a disaccharide: galactose and N-acetylgalactosamine (GalNAc), usually linked to a serine or threonine residue in a protein or glycolipid. Its full structure is often described as Galβ1-3GalNAc, a β-galactosyl-linked disaccharide.
Synonyms: Galβ1-3GalNAcα; Thomsen-Friedenreich; TF
Research Areas: Neuroscience
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