Full Name: Interleukin 2 Receptor Subunit Alpha
BACKGROUND: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
Synonyms: Interleukin 2 Receptor Subunit Alpha; IL2RA
Research Areas: Immunology
Amerigo scientific offers a comprehensive range of antibodies target IL2RA. Use the filter to find the IL2RA antibody that best fits your needs.
