Full Name: Integrin alpha 5 beta 1
BACKGROUND: Integrin α5β1 is an integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. It is composed of α5 (ITGA5/CD49e) and β1 (ITGB1/CD29) subunits. It is the primary receptor for fibronectin. The interaction of VLA-5 with fibronectin plays an important role in regulating inflammatory cytokine production by human articular chondrocytes (From the Cell Migration Gateway ITGA5 ITGB1).
Synonyms: Alpha-5 beta-1; α5β1; Integrin alpha 5 beta 1
Research Areas: Cardiovascular Biology
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