B. anthracis Lethal factor

B. anthracis Lethal factor

Target Overview

Full Name: Bacillus anthracis Lethal factor

BACKGROUND: Bacillus anthracis, the bacterium responsible for anthrax, secretes two primary toxins, one of which is the lethal factor. This toxin is a zinc-dependent metalloprotease that collaborates with the protective antigen (PA) to infiltrate host cells. Once inside, it cleaves mitogen-activated protein kinase kinases (MAPKKs), disrupting crucial cell signaling pathways. This disruption can result in cell death, tissue damage, and may lead to severe circulatory shock, posing a fatal risk to the infected host.

Synonyms: lef; LF; Lethal factor; Anthrax lethal toxin endopeptidase component; Bacillus anthracis Lethal factor

Research Areas: Microbiology

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Amerigo scientific offers a comprehensive range of antibodies targeting B. anthracis Lethal factor. Use the filter to find the B. anthracis Lethal factor antibody that best fits your needs.

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Catalog: ASPC908
Target : B. anthracis Lethal factor
Host Species : Human
Species Reactivity : Bacillus anthracis
Application : Enzyme-Linked Immunosorbent Assay
Catalog: ASPC909
Target : B. anthracis Lethal factor
Host Species : Human
Species Reactivity : Bacillus anthracis
Application : Enzyme-Linked Immunosorbent Assay
For Research Use Only.

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