Full Name: Varicella Zoster Virus
BACKGROUND: Varicella-Zoster Virus (VZV) gH/gL Complex is a critical component of the viral envelope that plays a key role in the virus's ability to infect host cells. The gH/gL complex interacts with other viral proteins, particularly gB (glycoprotein B), to mediate membrane fusion. gB is the actual fusogen, but its activity is regulated by the gH/gL complex. The interaction between gH/gL and specific receptors on the host cell surface triggers conformational changes that allow gB to drive the fusion process.
Synonyms: Varicella-zoster virus; VZV
Research Areas: Microbiology
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