Human blood coagulation Factor XIII-A2

- Overview
  - Recombinant pig Factor XIII is a homodimer (a2) composed of two chains held together by non covalent bonds. After activation of the zymogen by Thrombin and Ca2+ to its active form (a*2, Factor XIIIa), Factor XIIIa catalyzes the formation of covalent bridges (ε-(γ-glutamyl) lysine bonds) between fibrin units to increase the elasticity of the clot network. The resulting crosslinked fibrin is insoluble and resistant to lysis.
    
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- Properties
  - Name
    
    Recombinant Fibrin stabilizing factor, protein-glutamine-γ-glutamyltransferase
    
    Source
    
    Human embryonic kidney cells
    
    Type
    
    Recombinant Proteins
    
    Storage
    
    Storage for several months is possible at ≤ - 20°C.
    
    Note
    
    Intended for research use only, not for use in human, therapeutic or diagnostic applications.
    
    Molecular Weight
    
    83 kDa
    
    Class
    
    Human Factor XIII-A2
    
    Reconstitution
    
    Add the desired volume H2O to the vial of lyophilized powder. Rotate vial gently until solid dissolves. After reconstitution the solution should be cooled on ice for short termstorage. Storage for several weeks is possible at ≤ - 20°C.