1,3-Dimethyl-2-[(2-oxopropyl)thio]imidazolium chloride

- Overview
  - A weak blocker of tissue transglutaminase with an IC50 of about 1.0 μM
    
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- Properties
  - Molecular Weight
    
    220.72
    
    Storage
    
    Store at -20°C, desiccate
    
    * Intended for research use only, not for use in human, therapeutic or diagnostic applications.
- Applications
  - Application
    
    Transglutaminase inhibitors
    
    Application Description
    
    Inhibitor for transglutaminase
    D003 is a weak blocker of tissue transglutaminase with an IC50 of about 1.0 μM
- Reference
  - Freund, K. et al. Biochemistry 1994, 33, 10109.
    Skill, N.. et al. J. Biol. Chem. 2004, 279, 47754.
    Hugues L.-J. et al. J. Biol. Chem. 2012, 287, 18005.
    Sánchez-Lara A. et al. Vet Pathol. 2015, 52, 513.