Lamivudine

- Overview
  - Lamivudine (3TC) is a cytidine analog and antiretroviral medication commonly used to treat HIV and hepatitis B infections.
    
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    Background
    
    Lamivudine inhibits HIV reverse transcriptase and terminates DNA synthesis by competing for incorporation into viral DNA.
- Properties
  - CAS Number
    
    134678-17-4
    
    Molecular Formula
    
    C8H11N3O3S
    
    Molecular Weight
    
    229.26
    
    Other Properties
    
    Assay: 98.0 - 102.0%
    Heavy Metals: Not more than 20ppm
    Loss on Drying: Not more than 0.5%
    Absorbance: (440nm): Not more than 0.0015
    Melting Point: 175 - 179°C
    Optical Rotation: -135.0 - -145.0°
    Identification: Conforms to IR and HPLC
    
    Storage
    
    ≤30°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Lamivudine targets retroviruses hepatitis B virus (HBV) and human immunodeficiency virus (HIV).