Fusidic acid

- Overview
  - Fusidic acid is a bacteriostatic steroid antibiotic which targets protein synthesis in Gram-positive bacteria.
    
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    Background
    
    Fusidic acid inhibits protein synthesis by preventing translocation by inhibiting ribosomal elongation factor G.
- Properties
  - CAS Number
    
    6990-06-3
    
    Molecular Formula
    
    C31H48O6
    
    Molecular Weight
    
    516.72
    
    Appearance
    
    White or almost white, crystalline powder
    
    Other Properties
    
    Source: Fusidium coccineum
    Water Content (Karl Fischer): 1.4% - 2.0%
    Assay: (Anhydrous) 97.5% - 101.0%
    
    Storage
    
    2-8°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Fusidic acid targets Gram-positive bacteria namely those which cause skin infections.
    
    Microbiology Applications: Fusidic acid is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against gram positive microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options for infected patients. Representative MIC values include: Methicillin resistant Staphylococcus aureus (MRSA) 0.12 µg/mL - 1.0 µg/mL Streptococcus epidermidis 0.25 µg/mL