Terrein

- Overview
  - Terrein is a polar, substituted dihydrocyclopentenone first reported by Raistrick and colleagues in the 1930s and subsequently found in a number of Aspergillus and Penicillium species.
    
    Terrein is soluble in ethanol, methanol, DMF and DMSO.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Recent research shows that terrein reduces melanin synthesis by reducing tyrosinase production via ERK activation, followed by MITF down-regulation. Terrein also reduces human keratinocyte proliferation by inhibiting ERK and by decreasing the expression of cyclin B1 and Cdc2 complex.
- Properties
  - CAS Number
    
    582-46-7
    
    Molecular Formula
    
    C8H10O3
    
    Molecular Weight
    
    154.2
    
    Appearance
    
    Light tan solid
    
    Storage
    
    -20°C
    
    * For research use only