Neomycin Solution (10 mg/mL Neomycin in 0.9% NaCl)

Name: Neomycin Solution (10 mg/mL Neomycin in 0.9% NaCl)
Price: 197.00 USD

Catalog Number:

PB01342492TOK

Mfr. No.:

TOK-N027

Price:

$197

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- Overview
  - Neomycin Solution (10 mg/ml Neomycin in 0.9% NaCl) is a ready-to-use preparation of the broad-spectrum aminoglycoside antibiotic composed of related compounds including Neomycin A (neamine), Neomycin B (framycetin), Neomycin C, and a few minor compounds. Neomycin B is the most active, followed by C and A. The quantities of these components vary from lot-to-lot.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Aminoglycosides target the 30S ribosomal subunit resulting in an inability to read mRNA ultimately producing a faulty or nonexistent protein.
- Properties
  - CAS Number
    
    1405-10-3
    
    Molecular Formula
    
    C23H46N6O13
    
    Molecular Weight
    
    614.64
    
    Appearance
    
    Clear solution
    
    Solubility
    
    Solution
    
    Other Properties
    
    Source: Mixture
    
    Storage
    
    2-8 °C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Neomycin is a broad-spectrum antibiotic, however, it is mostly used against Gram-negative bacteria.
    
    Microbiology Applications: Neomycin can be used for gene selection, via exploiting the resistance gene (NPT II) (Aragão, 2009).
    Neomycin is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against Gram-positive and Gram-negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options. Representative effective ranges include:
    
    Pseudomonas aeruginosa 0.5 µg/mL – 64 µg/mL
    Haemophilus influenzae 1.6 µg/mL – 6.3 µg/mL
    
    Neomycin Sulfate can be used for food testing in TSN agar to select for Clostridium perfringins and inhibit growth of Enterobacteria and Clostridum bifermentans.
    
    Plant Biology Applications: Neomycin is commonly used in negative selections for plants which have been successfully been transformed with a plasmid conferring resistance via Agrobacterium mediated transformation.
    
    Eukaryotic Cell Culture Applications: Neomycin is routinely used to select for cells containing resistance plasmids such as pcDNA3 in common cell lines including AtT-20. For additional information please visit our cell-culture database.