Name: Marbofloxacin
Price: 193.00 USD

- Overview
  - Marbofloxacin is broad-spectrum, third-generation fluoroquinolone antibiotic commonly used in studying antimicrobial resistance and antimicrobial susceptibility testing. Marbofloxacin is freely soluble in water.
    
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    Background
    
    Fluoroquinolone antibiotics target bacterial DNA gyrase, an enzyme which reduces DNA strain during replication. DNA gyrase is required during DNA replication, thus causes an inhibition of DNA synthesis and cell division..
- Properties
  - CAS Number
    
    115550-35-1
    
    Molecular Formula
    
    C17H19FN4O4
    
    Molecular Weight
    
    362.36
    
    Appearance
    
    Light yellow crystalline powder
    
    Solubility
    
    Soluble in water
    
    Other Properties
    
    Source: Synthetic
    Assay: (On Dried Basis): 99.0-101.0%
    Loss on Drying: ≤0.5%
    Melting Point: 268-269°C
    Purity Level: ≥98.0%
    
    Storage
    
    2-8°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Marbofloxacin is a broad-spectrum antibiotic active against Gram-positive and Gram-negative bacteiria including Pseudomonas and Staphylococci species. It is also active against Mycoplasma.
    
    Microbiology Applications: Marbofloxacin is commonly used for in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against Gram-positive and Gram-negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options.
    Representative MIC values include:
    Pseudomonas aeruginosa 0.5 µg/mL
    Staphylococcus aureus 0.25 µg/mL
    
    The in vitro activity of Marbofloxacin, a quinolone, was evaluated on 124 anaerobic human strains isolated from the gut and testing revealed that Marbofloxacin was similalr or superior to Ofloxacin for the whole anaerobes such as Enterococcus, Enterobacteriaceae, and Lactobacillus (Dubreuil et al, 1996).