Lovastatin (Mevinolin)

Lovastatin (Mevinolin)

Catalog Number:
MAR1341454TOK
Mfr. No.:
TOK-L013
Price:
$222
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      • Overview
        • Lovastatin is a statin prodrug commonly used to combat hypercholesterolemia. Lovastatin inhibits HMG-CoA reductase, a significant enzyme involved in the cholesterol synthesis pathway. Lovastatin is insoluble in aqueous solution.

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          Background

          Lovastatin is an inhibitor of 3-hydroxy-3methylglutaryl-coenzyme A reductase (HMG-CoA reductase), an enzyme that catalyzes the conversion of HMG-CoA to mevalonate

      • Properties
        • CAS Number
          75330-75-5
          Molecular Formula
          C24H36O5
          Molecular Weight
          404.54
          Appearance
          White crystalline powder
          Solubility
          Water: 0.4 µg/mL
          Other Properties
          Source: Monascus Ruber
          Assay: 98.5-101.0%
          Loss on Drying: ≤0.3%
          Optical Rotation: +234° to +338°
          Purity Level: ≥95.0%
          Storage
          2-8°C

          * For research use only

      • Applications
        • Application Description
          Cancer Applications: Research has shown that statin drugs including lovastatin have been able to inhibit melanoma cell growth when high concentrations are used.

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