Name: Cefozopran Hydrochloride
Price: 429.00 USD

- Overview
  - Cefozopran Hydrochoride is a broad-spectrum, fourth-generation cephalosporin that interferes with bacterial peptidoglycan synthesis. The product is freely soluble in DMSO and slightly soluble in water.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Similar to β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases.
- Properties
  - CAS Number
    
    113981-44-5
    
    Molecular Formula
    
    C19H17N9O5S2•HCl
    
    Molecular Weight
    
    551.99
    
    Solubility
    
    Freely soluble in DMSO. Slightly soluble in water.
    
    Storage
    
    -20°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Cefozopran is a broad-spectrum antibiotic targeting a wide range of Gram-positive and Gram-negative bacteria including Pseudomonas aeruginosa.
    
    Microbiology Applications: Cefozopran has been shown to be useful against the multi drug resistant MRSA when used in combination with other antibiotics including vancomycin and teicoplanin.