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Boc-DON-Gln-Ile-Val-OMe, Boc-DON

Boc-DON-Gln-Ile-Val-OMe, Boc-DON

Catalog Number:

I001055217ZED

Mfr. No.:

B003

Price:

$736

Size:

10 mg

Quantity:

Add to Cart:

- Overview
  - Boc-DON is a potent and specific blocker of tissue transglutaminase (IC50 about 0.3 μM) and is not membrane permeable.
    
    Please contact us at for specific academic pricing.
- Properties
  - Alternative Name
    
    tert.-Butyloxycarbonyl-(6-Diazo-5-oxonorleucinyl)-LGlutaminyl-L-Isoleucinyl-L-Valinmethylester
    
    Molecular Weight
    
    625.7
    
    Appearance
    
    yellow solid
    
    Purity
    
    >95 % (HPLC)
    
    Storage
    
    store at -20°C, desiccate
    
    * Intended for research use only, not for use in human, therapeutic or diagnostic applications.
- Applications
  - Application
    
    Transglutaminase inhibitors
    
    Application Description
    
    Irreversible inhibitor of tissue transglutaminase; IC50 ~ 0.3 μM
- Reference
  - Verhaar et al., Neurochem. Int. 2011, 58:785-93
    Schaertl et al., J. Biomol. Screen. 2010, 15:478-87
    McConoughey et al., EMBO Mol. Med. 2010, 2:1-22
    Zeugolis et al., J. Biomed. Mater. Res. 2010, 15:1310-20
    Kristen et al., Circ. Res. 2008, 102:529-37
    Mádi et al., Anal. Biochem. 2005, 343:256-62

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