Boc-DON-Gln-Ile-Val-OMe, Boc-DON

Boc-DON-Gln-Ile-Val-OMe, Boc-DON

Catalog Number:
I001055217ZED
Mfr. No.:
B003
Price:
$771
  • Size:
    10 mg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • Boc-DON is a potent and specific blocker of tissue transglutaminase (IC50 about 0.3 μM) and is not membrane permeable.

          Please contact us at for specific academic pricing.

      • Properties
        • Alternative Name
          tert.-Butyloxycarbonyl-(6-Diazo-5-oxonorleucinyl)-LGlutaminyl-L-Isoleucinyl-L-Valinmethylester
          Molecular Weight
          625.7
          Appearance
          yellow solid
          Purity
          >95 % (HPLC)
          Storage
          store at -20°C, desiccate

          * Intended for research use only, not for use in human, therapeutic or diagnostic applications.

      • Applications
        • Application
          Transglutaminase inhibitors
          Application Description
          Irreversible inhibitor of tissue transglutaminase; IC50 ~ 0.3 μM
      • Reference

        • Verhaar et al., Neurochem. Int. 2011, 58:785-93
          Schaertl et al., J. Biomol. Screen. 2010, 15:478-87
          McConoughey et al., EMBO Mol. Med. 2010, 2:1-22
          Zeugolis et al., J. Biomed. Mater. Res. 2010, 15:1310-20
          Kristen et al., Circ. Res. 2008, 102:529-37
          Mádi et al., Anal. Biochem. 2005, 343:256-62

    Datasheet
    MSDS

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