Anti-MMP9 antibody

Catalog Number:

A001020751STJ

Mfr. No.:

STJ113539

Price:

$297

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Overview
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 538-707 of human MMP9 (NP_004985. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Matrix Metalloproteinase-9; Mmp-9; 92 Kda Gelatinase; 92 Kda Type Iv Collagenase; Gelatinase B; Gelb Cleaved Into-67 Kda Matrix Metalloproteinase-9-82 Kda Matrix Metalloproteinase-9 (Gene ID:4318; UniProt:P14780)
  
  * For research use only