Name: Anti-CD44 antibody
Price: 867.00 USD

Overview
- CD44 cell surface antigen is a 100 kDa type 1 transmembrane glycoprotein widely expressed on humanleucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Severalisoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues.CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion andmigration. CD44 also participates in a wide variety of cellular functions including lymphocyteactivation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential. CD44 is expressed byhematopoietic, non-hematopoietic cells, epithelial tissues, and to filopodia in cultured keratinocytes.Further, bone marrow myeloid cells and memory T cells express CD44 at high levels, and peripheral Band T cells can upregulate the expression of CD44 in response to certain stimulatory events.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG2b
  
  Reactivity
  
  human
  
  Clone
  
  MEM-85
  
  Conjugate
  
  PE
  
  Formulation
  
  0.5 ml purified antibody, conjugated to R-PE, in Phosphate buffered saline solution containing 4mg/mL BSA, sucrose and 0.1% sodium Azide.
  
  Storage
  
  Store antibody at 2-8°C until expiry. Avoid prolonged exposure to light.
  
  Concentration
  
  +/-150 µg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Cd44 Antigen; Cdw44; Epican; Extracellular Matrix Receptor III; Ecmr-III; Gp90 Lymphocyte Homing/Adhesion Receptor; Hutch-I; Heparan Sulfate Proteoglycan; Hermes Antigen; Hyaluronate Receptor; Phagocytic Glycoprotein 1; Pgp-1; Phagocytic Glycoprotein I; Pgp-I; Cd Antigen Cd44 (Gene ID:960; UniProt:P16070)
  
  * For research use only