-
-
Overview
-
The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being thestandard 85-95 kD or hematopoietic variant (CD44s) that is found in mesodermal cells such ashematopoietic, fibroblastic, and glial cells, as well as in some carcinoma cell lines. Higher molecularweight isoforms have been described in epithelial cells (CD44v) and are thought to function inintercellular adhesion and stromal binding. While many human tumors express CD44, a positivecorrelation between CD44v expression and tumor dedifferentiation has been demonstrated. may be useful in discrimination of urothelial carcinoma in-situ from non-neoplastic changes inthe urothelium.
Please contact us at for specific academic pricing.
-
- Properties
- Applications
-
Overview