-
-
Overview
-
In normal breast tissue, 304‐1A5 labels breast ductal and lobular epithelial cells. In tumor cells, it is reactive with all types of breast adenocarcinoma regardless tumor differentiation and types. Adenocarcinomas from other organs rarely express mammaglobin. Cellular localization: cytoplasmic. Mammaglobin is a breast‐associated glycoprotein distantly related to secretoglobin family that includes human uteroglobin and lipophilin. Unlike other secretoglobin family members, mammaglobin mRNA expression is breast specific, which has been shown to be a very sensitive marker of occult breast cancer cells in sentinel lymph nodes (Figure 1) and peripheral blood. By paraffin immunohistochemistry, the overall sensitivity of mammaglobin for breast cancers (Figure 2) was reported about 80%. When combined with other breast‐restricted markers such as GCDFP‐15, an overall sensitivity of 84% could be achieved. Mammaglobin can play a contributing role in the identification of primary sites of carcinomas presenting at metastatic sites. Positive control: normal human breast tissue.
Please contact us at for specific academic pricing.
-
- Properties
- Applications
-
Overview
The sensitivity of mammagloblin for breast cancers,Figure 2 was about 80%. Combined with breast-restricted markers such as GCDFP-15, a sensitivity of 84% is achieved. Mammaglobin can play a role identifying of sites of carcinomas at metastatic sites The sensitivity of mammagloblin for breast cancers,Figure 2 was about 80%. Combined with breast-restricted markers such as GCDFP-15, a sensitivity of 84% is achieved. Mammaglobin can play a role identifying of sites of carcinomas at metastatic sites The sensitivity of mammagloblin for breast cancers,Figure 2 was about 80%. Combined with breast-restricted markers such as GCDFP-15, a sensitivity of 84% is achieved. Mammaglobin can play a role identifying of sites of carcinomas at metastatic sites The sensitivity of mammagloblin for breast cancers,Figure 2 was about 80%. Combined with breast-restricted markers such as GCDFP-15, a sensitivity of 84% is achieved. Mammaglobin can play a role identifying of sites of carcinomas at metastatic sites
Anti-Mammaglobin antibody
Anti-Mammaglobin antibody
Catalog Number:
IGA1029367STJ
Mfr. No.:
STJ180162
Price:
$361
Size:
Quantity:
Add to Cart:
.